Founded by radiation biologists and commercially launched in 2015 with funding from NASA, KromaTiD’s genesis is rooted in tracking radiation induced structural rearrangements over time. dGH SCREEN, the original KromaTiD assay, was initially utilized by NASA to monitor the effects of ionizing deep space radiation in their astronauts.
Today, dGH SCREEN is still being used by NASA to assess structural rearrangements in the genomes of their best and brightest. dGH SCREEN’s unique single stranded design allows researchers to visualize and quantify inversions as an inherently more stable biodismeter than dicentrics, which enables them to obtain data much longer after a radiation event. In addition to greater stability, inversions occur with lower background frequency than other symmetrical aberrations such as translocations, providing fewer false positives and more reliable data.
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